Desitin rapid relief cream is a smooth and creamy diaper rash treatment that contains zinc oxide, known to block moisture from baby's skin. The barrier cream forms a protective layer on your baby's skin to soothe and relieve diaper rash discomfort, providing relief from the very first use. In fact, over 88 percent of moms agree that nothing works faster. Our hypoallergenic, dermatologist-tested formula goes on smoothly and wipes off easily, making desitin rapid relief cream your everyday partner in protecting against and treating diaper rash for relief your baby can feel. Creamy formula that glides on smoothly and wipes off easily. Helps heal, soothe, and prevent diaper rash. 1 Choice of pediatricians and moms. Provides moisturization and emolliency to the skin. Acts as an anti-inflammatory, reducing redness and irritation of sensitive and inflammatory-prone skin.