NeilMed NasaFlo Neti Pot comes with 50 packets of easy to dispense USP Grade (99.9% pure) and preservative free sodium chloride and sodium bicarbonate mixture. It is pH balanced & isotonic for maximum comfort. Smooth gravity flow creates no pressure in the nasal passage, ears or sinuses. each packet contains precisely measure mixture to mix with 8 oz (240 m - L) of lukewarm distilled water, taking the guesswork out of preparing this solution. This box also contains step by step directions for use and extensive educational material on nasal and sinus disease.